However, this is a case where you’ll want to use your common sense. If you went to college for marketing and had a marketing internship your senior year, then worked as a server for the next several years, you would want to include your marketing internship.
A resume is the representation of your professional self. It is a concise compilation of your educational and professional experience, as well as the skills that make you desirable for the workforce. It is what you use to sell your merit and skills to potential employers.