In the short term, you should tweak your resume based on each job you apply to. For example, if one position you’re applying to seems to weigh a certain responsibility or focus over another, you should be sure your resume conveys your expertise in this area. At the same time, you should be updating your resume with your experience as it develops, adding any new skills you’ve learned, courses you’ve taken or awards you won.
A resume is the representation of your professional self. It is a concise compilation of your educational and professional experience, as well as the skills that make you desirable for the workforce. It is what you use to sell your merit and skills to potential employers.