However, this is a case where you’ll want to use your common sense. If you went to college for marketing and had a marketing internship your senior year, then worked as a server for the next several years, you would want to include your marketing internship.
Some companies will indicate that they want you to submit a CV rather than a resume. A CV and a resume are not the same. CV stands for “curriculum vitae” and is meant to be an expansion of your resume. It is much longer than a resume, often three pages or more, and focuses mainly on your academic and professional accomplishments, with a particular focus on education.