In the short term, you should tweak your resume based on each job you apply to. For example, if one position you’re applying to seems to weigh a certain responsibility or focus over another, you should be sure your resume conveys your expertise in this area. At the same time, you should be updating your resume with your experience as it develops, adding any new skills you’ve learned, courses you’ve taken or awards you won.
Also be sure to include your city, state or zip code in your contact info, since employers will sometimes search Applicant Tracking Systems with these criteria. It’s also important for ATS to have this information at the top of your page, otherwise it may not be parsed into your candidate profile, making it harder for HR to find or remember your resume.