One of the biggest mistakes you can make when applying to jobs is sending the same generic resume out for each one. Sure, you can apply to more jobs if you don’t take the time to personalize your resume each time, but chances are you won’t get interviews from any of them. If you take the time to tailor your resume, even though you’ll be applying for fewer jobs, you’ll get more interviews.
Some companies will indicate that they want you to submit a CV rather than a resume. A CV and a resume are not the same. CV stands for “curriculum vitae” and is meant to be an expansion of your resume. It is much longer than a resume, often three pages or more, and focuses mainly on your academic and professional accomplishments, with a particular focus on education.