In the short term, you should tweak your resume based on each job you apply to. For example, if one position you’re applying to seems to weigh a certain responsibility or focus over another, you should be sure your resume conveys your expertise in this area. At the same time, you should be updating your resume with your experience as it develops, adding any new skills you’ve learned, courses you’ve taken or awards you won.
There is not one resume format that works for everyone. There might not even be only one resume format for you and it could benefit you to have multiple formats of your resume available. For example, if you’re applying for a job and you don’t know whether your resume will be submitted through ATS, submit both a chronological resume and use a functional resume for your in person interview.