One of the biggest mistakes you can make when applying to jobs is sending the same generic resume out for each one. Sure, you can apply to more jobs if you don’t take the time to personalize your resume each time, but chances are you won’t get interviews from any of them. If you take the time to tailor your resume, even though you’ll be applying for fewer jobs, you’ll get more interviews.
When writing the descriptions for the jobs you’ve held, focus on what you accomplished in each position rather than what you did. Listing quantifiable achievements in a numerical manner (increased sales 20%, reduced expenses by 10%, for example) will help your resume stand out.